DPY19L1 antibody (AA 571-675) (HRP)

Catalog No. ABIN1416106

Product Details anti-DPY19L1 Antibody (HRP)

Target: DPY19L1 (Dpy-19-Like 1 (C. Elegans) (DPY19L1))

Binding Specificity: AA 571-675

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPY19L1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DPY19L1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DPY19L1

Target: DPY19L1 (Dpy-19-Like 1 (C. Elegans) (DPY19L1))

Alternative Name: DPY19L1 (DPY19L1 Products)

Synonyms: 1100001I19Rik antibody, 6030402K12 antibody, AI225861 antibody, AW558481 antibody, RGD1305822 antibody, dpy-19 like C-mannosyltransferase 1 antibody, probable C-mannosyltransferase DPY19L1 antibody, dpy-19 like 1 antibody, dpy-19-like 1 (C. elegans) antibody, DPY19L1 antibody, LOC100011919 antibody, dpy19l1 antibody, Dpy19l1 antibody

Background:

Synonyms: D19L1_HUMAN, Dpy 19 like 1 C. elegans, Dpy 19 like protein 1, Dpy-19-like protein 1, DPY19L1, GA0500, KIAA0877, Protein dpy 19 homolog 1, Protein dpy-19 homolog 1, Protein dpy19 homolog 1.

Background: Dpy-19 (dumpy-19), is a 683 amino acid C. elegans protein that is required to orient the neuroblasts QL and QR correctly on the anterior/posterior axis. Dpy-19 is expressed highly in dorsal hyp7 cells, ventral P cells and lateral V cells, and dorsal and ventral body muscle cells. DPY19L1 (Dpy-19-like protein 1), also known as KIAA0877, is a 675 amino acid multi-pass membrane protein that belongs to the Dpy-19 family. DPY19L1 is expressed as two isoforms produced by alternative splicing and is encoded by a gene mapping to human chromosome 7, which encodes over 1,000 genes and makes up about 5 % of the human genome. Diseases associated with chromosome 7 include Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Gene ID: 23333

Pathways: SARS-CoV-2 Protein Interactome