TPP1 antibody (AA 401-500) (HRP)

Catalog No. ABIN1417444

Product Details anti-TPP1 Antibody (HRP)

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Binding Specificity: AA 401-500

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPP1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TPP1/CLN2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Alternative Name: TPP1 (TPP1 Products)

Synonyms: cln2 antibody, fa01b09 antibody, im:7149243 antibody, wu:fa01b09 antibody, CLN2 antibody, LPIC antibody, TPP-1 antibody, TPP-I antibody, Cln2 antibody, tripeptidyl peptidase I antibody, tripeptidyl-peptidase 1 antibody, tripeptidyl peptidase 1 antibody, tpp1 antibody, NAEGRDRAFT_78259 antibody, MCYG_00184 antibody, MGYG_05881 antibody, MGYG_00757 antibody, TPP1 antibody, Tpp1 antibody

Background:

Synonyms: Cell growth inhibiting gene 1 protein, Cell growth-inhibiting gene 1 protein, Ceroid lipofuscinosis neuronal 2, Ceroid lipofuscinosis neuronal 2 late infantile Jansky Bielschowsky disease, Ceroid lipofuscinosis neuronal 2 late infantile antibody CLN 2, CLN2, CLN-2, GIG 1, GIG1, Growth inhibiting protein 1, LPIC, Lysosomal pepstatin insensitive protease, Lysosomal pepstatin-insensitive protease, TPP 1, TPP I, TPP-1, TPP-I, Tpp1, TPP1_HUMAN, TPPI, Tripeptidyl aminopeptidase, Tripeptidyl peptidase I, Tripeptidyl-peptidase 1, Tripeptidyl-peptidase I.

Background: Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus.

Gene ID: 1200

Pathways: Cell Division Cycle, ER-Nucleus Signaling