PSMB3 antibody (HRP)

Catalog No. ABIN1420132

Product Details anti-PSMB3 Antibody (HRP)

Target: PSMB3 (Proteasome Subunit beta 3 (PSMB3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB3 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Proteasome 20S beta 3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PSMB3

Target: PSMB3 (Proteasome Subunit beta 3 (PSMB3))

Abstract: PSMB3 Products

Synonyms: HC10-II antibody, AL033320 antibody, C10-II antibody, PSB3 antibody, psmb3 antibody, wu:fb11d10 antibody, wu:fu88b08 antibody, zgc:56374 antibody, DDBDRAFT_0190542 antibody, DDBDRAFT_0232932 antibody, DDB_0190542 antibody, DDB_0232932 antibody, proteasome subunit beta 3 antibody, proteasome (prosome, macropain) subunit, beta type 3 antibody, proteasome subunit C10-11 antibody, proteasome subunit beta type-3 antibody, proteasome subunit beta 3 S homeolog antibody, 20S proteasome subunit beta-3 antibody, PSMB3 antibody, Psmb3 antibody, LOC100135869 antibody, LOC399377 antibody, psmb3.S antibody, psmb3 antibody, psmB3 antibody

Background:

Synonyms: 20S Proteasome _3, C10 II, HC10 II, proteasome prosome, macropain subunit, beta type 3, Proteasome beta 3 subunit, Proteasome chain 13, proteasome component C10 II, Proteasome theta chain, PSMB3.

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.

Gene ID: 5684

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Cell RedoxHomeostasis, Lipid Metabolism