DENND4C antibody (HRP)

Catalog No. ABIN1421854

Product Details anti-DENND4C Antibody (HRP)

Target: DENND4C (DENN/MADD Domain Containing 4C (DENND4C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND4C antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DENND4C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DENND4C

Target: DENND4C (DENN/MADD Domain Containing 4C (DENND4C))

Alternative Name: DENND4C (DENND4C Products)

Synonyms: 1700065A05Rik antibody, AA420392 antibody, C9orf55 antibody, C9orf55B antibody, bA513M16.3 antibody, DENN domain containing 4C antibody, DENN/MADD domain containing 4C antibody, DENND4C antibody, Dennd4c antibody

Background:

Synonyms: C9orf55, C9orf55B, DEN4C_HUMAN, DENN domain-containing protein 4C, DENN/MADD domain containing 4C, DENND4C.

Background: DENND4C is a 1,673 amino acid multi-pass membrane protein. DENND4C contains a dDENN domain, DENN domain, uDENN domain and a PPR (pentatricopeptide) repeat. As a result of alternative splicing, six DENND4C isoforms exist. The gene encoding DENND4C maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Gene ID: 55667