5HT1D antibody (PE)

Catalog No. ABIN1429460

The Rabbit Polyclonal anti-5HT1D antibody has been validated for FACS. It is suitable to detect 5HT1D in samples from Mouse, Human and Rat.

Quick Overview for 5HT1D antibody (PE) (ABIN1429460)

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 5HT1D antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-5HT1D Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT1D Receptor/SR-1D

Isotype: IgG

Application Details

Application Notes: FCM: 1:20-100
Optimal working dilution should be determined by the investigator.

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4 °C

Expiry Date: 12 months

Target Details for 5HT1D

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Background:

The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1â€"7 (5HT1â€"7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Subcellular location: Extracellular

Synonyms: 5 HT 1D alpha, 5 HT 1D, 5 HT1B, 5 HT1D, 5HT1D, 5 hydroxytryptamine serotonin receptor 1B, 5 hydroxytryptamine serotonin receptor 1D G protein coupled, 5 hydroxytryptamine 1B receptor 5 HT 1B Serotonin receptor 5 HT 1D beta Serotonin 1D beta receptor S12, 5 hydroxytryptamine receptor 1D, HT1DA, HTR1D, HTR1D2, HTR1DA, HTRL, RDC4, S12, Serotonin receptor 1D, 5HT1D_HUMAN.

Pathways: JAK-STAT Signaling