FNDC5 antibody (PE)

Catalog No. ABIN1433177

There is 1 publication for this product available. The Rabbit Polyclonal anti-FNDC5 antibody is suitable to detect FNDC5 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for FNDC5 antibody (PE) (ABIN1433177)

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNDC5 antibody is conjugated to PE

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FNDC5 Antibody (PE)

Purpose: FNDC5 Polyclonal Antibody, PE Conjugated

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FNDC5 Irisin

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-FNDC5 antibody (PE) (ABIN1433177)

Park, Kim, Choi, Heo, Park: "New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro." in: Cellular signalling, Vol. 27, Issue 9, pp. 1831-9, (2015) (PubMed).

Target Details for FNDC5

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Alternative Name: FNDC5

Background:

Synonyms: FRCP2, irisin, Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, FNDC5

Background: Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.

Gene ID: 252995

UniProt: Q8NAU1

Pathways: Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation