N-Cadherin antibody (C-Term)

Catalog No. ABIN1440032

The Goat Polyclonal anti-N-Cadherin antibody is suitable to detect N-Cadherin in samples from Human, Mouse, Rat, Chicken, Cow, Rabbit, Dog, Pig, Monkey, Horse, Sheep, Cat, Donkey, Goat, Guinea Pig, Hamster and Avian. It has been validated for WB and IF.

Quick Overview for N-Cadherin antibody (C-Term) (ABIN1440032)

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reactivity: Human, Mouse, Rat, Chicken, Cow, Rabbit, Dog, Pig, Monkey, Horse, Sheep, Cat, Donkey, Goat, Guinea Pig, Hamster, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This N-Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-N-Cadherin Antibody

Binding Specificity: C-Term

Purpose: Anti-CDH2

Sequence: VFDYEGSGST AGSLSSLNSS SSGGEQDYDY LNDWGPRFKK LADMYGGGDD

Specificity: Detects endogenous levels of total N-cadherin protein by Western blot in the whole cell lysates (COS-7, HeLa, HUH and Hepa-6).

Characteristics: N-Cadherin

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 850 aa to C-terminus of human CDH2 produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000, IF:1:25-1:250

Restrictions: For Research Use only

Handling

Concentration: 3 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for N-Cadherin

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Alternative Name: CDH2

Background:

Goat polyclonal to CDH2. CDH2 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one trans membrane domain, and a highly conserved intracellular domain. It has been shown to play an essential role in normal neuronal development, which is implicated in an array of processes including neuronal differentiation, migration, axon growth and fasciculation.

cadherin 2, cadherin-2, CD325, CDHN, CDw325, CDH2, NCAD, N-cadherin, N-cadherin 1, neural cadherin, neural-cadherin, neural cadherin (NCAD) antibody.

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane