HNRNPA2B1 antibody
Quick Overview for HNRNPA2B1 antibody (ABIN1449240)
Target
See all HNRNPA2B1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody reacts with hnRNP-A2/B1.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse
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Immunogen
- Protein fraction extracted from the mitotic chromosome
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Isotype
- IgM
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Upon receipt, store (in aliqouts) at -20 °C.
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- HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))
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Alternative Name
- HnRNP-A2/B1 / HNRNPA2B1
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Background
- The heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) was recently shown to be up-regulated in th e early stage of lung cancer. This protein plays an important role in biogenesis and transport of mRNA. Up-regulation of hnRNP usually precedes morphological differentiation and is considered a good biomarker in the early stages of cancer development. HnRNP-A2/B1 proteins were localized primarily in the nucleus, excluding the nucleolus, although the expression of A2 protein was weaker than that of B1 protein. hnRNP-A2/B1 proteins were apparently expressed in nonmalignant alveolar cells as well as cancer cells, although the expression in alveolar cells was weaker than that of cancer cells.Synonyms: HNRPA2B1, Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNP A2 / hnRNP B1
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Molecular Weight
- 40 kDa
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Gene ID
- 3181
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NCBI Accession
- NP_002128
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UniProt
- P22626
Target
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