CDK1 antibody (AA 30-57, AA 42-49)

Catalog No. ABIN1449303

The Mouse Monoclonal anti-CDK1 antibody (Clone 5F6) (ABIN1449303) specifically detects CDK1 in WB, IP and IHC (p). The antibody is reactive with Human, Mouse, Rat and Rabbit samples.

Quick Overview for CDK1 antibody (AA 30-57, AA 42-49) (ABIN1449303)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivity: Human, Mouse, Rat, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5F6

Product Details anti-CDK1 Antibody

Binding Specificity: AA 30-57, AA 42-49

Sequence: EGVPSTAI

Specificity: This antibody reacts with Cdc2. The epitope of 5F6 exists between amino acids 42 and 49 of Cdc2 (EGVPSTAI).

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat, Hamster.

Purification: Protein A agarose

Immunogen: KLH conjugated Cdc2 peptide (30-57 aa)

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store (in aliqouts) at -20 °C.

Target Details for CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Alternative Name: CDK1

Background: Cell division cycle 2 (Cdc2) also named p34cdc2 or Cdk1 is a catalytic subunit of a protein kinase complex, called the M-phase promoting factor that induces entry into mitosis and is universal among eukaryotes. In the fission yeast Schizosaccharomyces pombe, the gene Cdc2 is responsible for controlling the transition from G1 phase to the S phase and from the G2 phase to the M phase of the cell cycle.Synonyms: CDC2, CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase

Gene ID: 983

NCBI Accession: NP_001777

UniProt: P06493

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA