IL-3 antibody

Catalog No. ABIN1449364

This Mouse Monoclonal antibody specifically detects IL-3 in WB, Neut and EIA. It exhibits reactivity toward Human.

Quick Overview for IL-3 antibody (ABIN1449364)

Target: IL-3 (Interleukin 3 (IL-3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-3 antibody is un-conjugated

Application: Western Blotting (WB), Neutralization (Neut), Enzyme Immunoassay (EIA)

Product Details anti-IL-3 Antibody

Purification: Affinity Chromatography on Protein G

Immunogen: Highly purified E.coli derived Recombinant Human IL-3 (Cat.-No PA076)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of 1.0 mg/mL.

Buffer: PBS without preservatives

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IL-3

Target: IL-3 (Interleukin 3 (IL-3))

Alternative Name: Interleukin-3 / IL3

Background: IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.Synonyms: Hematopoietic growth factor, IL-3, MCGF, Mast cell growth factor, Multipotential colony-stimulating factor, P-cell-stimulating factor

Gene ID: 3562

NCBI Accession: NP_000579

UniProt: P08700

Pathways: JAK-STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy