SGSM1 antibody (Middle Region)

Catalog No. ABIN1449980

The Rabbit Polyclonal anti-SGSM1 antibody is suitable to detect SGSM1 in samples from Human, Mouse and Rat. It has been validated for WB, IF and EIA.

Quick Overview for SGSM1 antibody (Middle Region) (ABIN1449980)

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGSM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-SGSM1 Antibody

Binding Specificity: Middle Region

Purification: Affinity chromatography purified via peptide column

Immunogen: SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for SGSM1

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Alternative Name: SGSM1

Background: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.Synonyms: RUTBC2, Small G protein signaling modulator 1

Molecular Weight: 126 kDa

Gene ID: 129049

NCBI Accession: NP_001035037