SGSM1 antibody (AA 480-530)

Catalog No. ABIN6991753

Product Details anti-SGSM1 Antibody

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Binding Specificity: AA 480-530

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGSM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: At least four isoforms of SGSM1 are known to exist, SGSM1 antibody will detect all four isoforms.

Purification: SGSM1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1. The immunogen is located within amino acids 480 - 530 of SGSM1.

Isotype: IgG

Application Details

Application Notes: SGSM1 antibody can be used for detection of SGSM1 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SGSM1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SGSM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SGSM1

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Alternative Name: SGSM1 (SGSM1 Products)

Synonyms: RUTBC2 antibody, 2410098H20Rik antibody, AA408781 antibody, D5Bwg1524e antibody, E130107M15 antibody, NuIP antibody, Rutbc2 antibody, small G protein signaling modulator 1 antibody, SGSM1 antibody, Sgsm1 antibody

Background: SGSM1 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.

Molecular Weight: 126 kDa

Gene ID: 129049

NCBI Accession: NP_001035037

UniProt: Q2NKQ1