Formin-Like 1 antibody (C-Term)
Quick Overview for Formin-Like 1 antibody (C-Term) (ABIN1450026)
Target
See all Formin-Like 1 (FMNL1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- A 16 amino acid peptide near the carboxy terminus of Human FRL1
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Formin-Like 1 (FMNL1)
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Alternative Name
- Formin-Like Protein 1
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Background
- The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.Synonyms: C17orf1, C17orf1B, CLL-associated antigen KW-13, FMNL, FMNL1, Leukocyte formin
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Molecular Weight
- 121 kDa
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Gene ID
- 752
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NCBI Accession
- NP_005883
Target
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