NSRP1 antibody (C-Term)

Catalog No. ABIN1450062

The Chicken Polyclonal anti-NSRP1 antibody (ABIN1450062) specifically detects NSRP1 in WB, IF and EIA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NSRP1 antibody (C-Term) (ABIN1450062)

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This NSRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-NSRP1 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the carboxy terminus of Human CCDC55

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NSRP1

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Alternative Name: CCDC55

Background: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection. Nuclear speckles are known to be the storage sites of mRNA splicing regulators. CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo. It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing. Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.Synonyms: Coiled-coil domain-containing protein 55, HSPC095, NSrp70

Gene ID: 84081

NCBI Accession: NP_115517