NSRP1
(Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))
Binding Specificity
AA 430-480, C-Term
Reactivity
Human, Mouse, Rat
Host
Chicken
Clonality
Polyclonal
Conjugate
This NSRP1 antibody is un-conjugated
Application
Western Blotting (WB), ELISA, Immunofluorescence (IF)
Specificity
At least three isoforms are known to exist, this antibody will detect all three.
Purification
CCDC55 Antibody is affinity chromatography purified via peptide column.
Immunogen
CCDC55 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CCDC55. The immunogen is located within amino acids 430 - 480 of CCDC55.
NSRP1
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
FITC
Application Notes
CCDC55 antibody can be used for detection of CCDC55 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
CCDC55 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
CCDC55 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
NSRP1
(Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))
CCDC55 Antibody: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection. Nuclear speckles are known to be the storage sites of mRNA splicing regulators. CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo. It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing. Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.