1600016B17Rik antibody, im:7154480 antibody, si:dz57f23.2 antibody, zgc:136957 antibody, Ras association domain family member 6 antibody, Ras association (RalGDS/AF-6) domain family member 6 antibody, Ras association (RalGDS/AF-6) domain family 6 antibody, RASSF6 antibody, Rassf6 antibody, rassf6 antibody
Background
RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NFk-B pathway and may play a vital role in infection.Synonyms: Ras association domain-containing protein 6