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FOXRED2 antibody (N-Term)

FOXRED2 Reactivity: Human EIA, IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1450133
$705.60
Plus shipping costs $45.00
0.1 mg
Shipping to: United States
Available
  • Target See all FOXRED2 Antibodies
    FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    Human
    Host
    • 8
    Rabbit
    Clonality
    • 8
    Polyclonal
    Conjugate
    • 4
    • 2
    • 1
    • 1
    This FOXRED2 antibody is un-conjugated
    Application
    • 7
    • 3
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid synthetic peptide near the amino terminus of Human FOXRED2
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))
    Alternative Name
    FOXRED2 (FOXRED2 Products)
    Synonyms
    ERFAD antibody, A430097D04Rik antibody, D15Bwg0759e antibody, Gm304 antibody, zgc:153216 antibody, RGD1306763 antibody, FAD dependent oxidoreductase domain containing 2 antibody, FAD-dependent oxidoreductase domain containing 2 antibody, FOXRED2 antibody, Foxred2 antibody, foxred2 antibody
    Background
    FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.Synonyms: FAD-dependent oxidoreductase domain-containing protein 2
    Gene ID
    80020
    Pathways
    SARS-CoV-2 Protein Interactome
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