GFRA3 antibody

Catalog No. ABIN1450226

Product Details anti-GFRA3 Antibody

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This GFRA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: The GFRa-3 is aglycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member ofthe GDNF receptor family. It forms a signaling receptor complex with RETtyrosine kinase receptor and binds the ligand, artemin

Characteristics: Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.

Purification: GFRα-3 affinity purified

Isotype: IgY

Application Details

Application Notes: Western immunoblotting, recommended dilution 1:5 000to 1:10 000, ELISA: 1:160 000 to 1:320 000, IF 1:1500 to1:3000. Polyclonal antibody working titer has to beestablished practically for each particular antigen and assay format

Comment:

Synonym: GDNF receptor alpha-3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml

Buffer: Concentrated ammonium sulphate in PBS pH 7.4

Handling Advice: As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use

Storage: 4 °C

Storage Comment: This product is shipped in non-frozen liquid form in ambient conditions

Target Details for GFRA3

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Alternative Name: GFRa-3 (GFRA3 Products)

Synonyms: GFRA3 antibody, GFRalpha3 antibody, Y15110 antibody, GDNF family receptor alpha 3 antibody, glial cell line derived neurotrophic factor family receptor alpha 3 antibody, Gfra3 antibody, GFRA3 antibody

Background: Recombinant His-tagged human GFRa-3 protein producedusing CHO-based cell line. For production of hGFRa-3, glycosylphosphatidyl-inositol GPI-anchor was removedand protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant

UniProt: O60609