VAV1 antibody (pTyr160)

Catalog No. ABIN1450278

The Rabbit Polyclonal anti-VAV1 antibody (ABIN1450278) specifically detects VAV1 in ELISA and IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for VAV1 antibody (pTyr160) (ABIN1450278)

Target: VAV1 (Vav 1 Oncogene (VAV1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAV1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-VAV1 Antibody

Binding Specificity: AA 131-180, pTyr160

Specificity:

VAV1 (Phospho-Tyr160) Antibody detects endogenous levels of VAV1 only when phosphorylated at Tyr160.

PhosphorylationH:Y160, M:Y160, R:Y160

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from human VAV1 around the phosphorylation site of Tyr160.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for VAV1

Target: VAV1 (Vav 1 Oncogene (VAV1))

Alternative Name: VAV1

Background:

Synonyms: Proto-oncogene vav, VAV1, VAV

NCBI Gene Symbol: VAV

Molecular Weight: 98 kDa

Gene ID: 7409

OMIM: 164875

UniProt: P15498

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling