SNCA antibody (pTyr125)

Catalog No. ABIN1450389

The Rabbit Polyclonal anti-SNCA antibody (ABIN1450389) specifically detects SNCA in ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SNCA antibody (pTyr125) (ABIN1450389)

Target: SNCA (Synuclein, alpha (SNCA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNCA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-SNCA Antibody

Binding Specificity: AA 91-140, pTyr125

Specificity:

Synuclein-alpha (Phospho-Tyr125) Antibody detects endogenous levels of Synuclein-alpha only when phosphorylated at Tyr125.

PhosphorylationH:Y125, M:Y125, R:Y125

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from human Synuclein-alpha around the phosphorylation site of Tyr125.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Alternative Name: Synuclein-alpha

Background:

Synonyms: Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, SNCA, NACP, PARK1

NCBI Gene Symbol: SNCA

Molecular Weight: 14 kDa

Gene ID: 6622

OMIM: 127750

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity