BIM antibody (pSer59)

Catalog No. ABIN1450464

The Rabbit Polyclonal anti-BIM antibody (ABIN1450464) specifically detects BIM in IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BIM antibody (pSer59) (ABIN1450464)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIM antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-BIM Antibody

Binding Specificity: AA 31-80, pSer59

Specificity:

BIM (Phospho-Ser59) Antibody detects endogenous levels of BIM only when phosphorylated at Ser59.

PhosphorylationH:S59, M:S55, R:S55

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from human BIM around the phosphorylation site of Ser59.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Alternative Name: BIM

Background:

Synonyms: Bcl-2 related ovarian death protein, BCL2 interacting mediator of cell death, Bcl2 interacting mediator of cell death, BCL2-like protein 11, Bcl2-like protein 11, BCL2L11, BOD

NCBI Gene Symbol: BCL2L11

Molecular Weight: 22 kDa

Gene ID: 10018

OMIM: 603827

UniProt: O43521

Pathways: PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity