HDAC7 antibody (pSer155)

Catalog No. ABIN1450530

The Rabbit Polyclonal anti-HDAC7 antibody (ABIN1450530) specifically detects HDAC7 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HDAC7 antibody (pSer155) (ABIN1450530)

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HDAC7 Antibody

Binding Specificity: AA 121-170, pSer155

Purpose: HDAC7 (phospho Ser155) Antibody

Specificity: Phospho-HDAC7 (S155) Polyclonal Antibody detects endogenous levels of HDAC7 protein only when phosphorylated at S155.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human HDAC7A around the phosphorylation site of Ser155. AA range:121-170

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HDAC7

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Alternative Name: HDAC7A

Background:

Synonyms: HDAC7, HDAC7A, Histone deacetylase 7, HD7, Histone deacetylase 7A, HD7a

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: HDAC7

Protein Name: Histone deacetylase 7

Molecular Weight: 102 kDa

Gene ID: 51564

OMIM: 606542

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development