PINX1 antibody (AA 121-170)

Catalog No. ABIN1450857

The Rabbit Polyclonal anti-PINX1 antibody (ABIN1450857) specifically detects PINX1 in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PINX1 antibody (AA 121-170) (ABIN1450857)

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINX1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PINX1 Antibody

Binding Specificity: AA 121-170

Purpose: PinX1 Antibody

Specificity: PinX1 Polyclonal Antibody detects endogenous levels of PinX1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PINX1. AA range:121-170

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PINX1

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Alternative Name: PINX1

Background:

Synonyms: PINX1, LPTL, LPTS, PIN2/TERF1-interacting telomerase inhibitor 1, Liver-related putative tumor suppressor, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1

Background: domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous, expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,

Gene Name: PINX1

Protein Name: PIN2/TERF1-interacting telomerase inhibitor 1

Molecular Weight: 37 kDa

Gene ID: 54984

OMIM: 606505

UniProt: Q96BK5