DOK5 antibody (AA 101-150)

Catalog No. ABIN1450881

The Rabbit Polyclonal anti-DOK5 antibody (ABIN1450881) specifically detects DOK5 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for DOK5 antibody (AA 101-150) (ABIN1450881)

Target: DOK5 (Docking Protein 5 (DOK5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DOK5 Antibody

Binding Specificity: AA 101-150

Purpose: Dok-5 Antibody

Specificity: Dok-5 Polyclonal Antibody detects endogenous levels of Dok-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human DOK5. AA range:101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DOK5

Target: DOK5 (Docking Protein 5 (DOK5))

Alternative Name: DOK5

Background:

Synonyms: DOK5, C20orf180, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6

Background: docking protein 5(DOK5) Homo sapiens The protein encoded byThis gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014],

Gene Name: DOK5

Protein Name: Docking protein 5

Molecular Weight: 35 kDa

Gene ID: 55816

OMIM: 608334

UniProt: Q9P104