IL17RA antibody (AA 141-190)

Catalog No. ABIN1450932

The Rabbit Polyclonal anti-IL17RA antibody (ABIN1450932) specifically detects IL17RA in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for IL17RA antibody (AA 141-190) (ABIN1450932)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RA Antibody

Binding Specificity: AA 141-190

Purpose: IL-17Rα Antibody

Specificity: IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human IL17RA. AA range:141-190

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL17RA

Background:

Synonyms: IL17RA, IL17R, Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CDw217, CD antigen CD217

Background: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

Gene Name: IL17RA

Protein Name: Interleukin-17 receptor A

Molecular Weight: 96 kDa

Gene ID: 23765

OMIM: 605461

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome