MRPS12 antibody (AA 21-70)

Catalog No. ABIN1450974

The Rabbit Polyclonal anti-MRPS12 antibody (ABIN1450974) specifically detects MRPS12 in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for MRPS12 antibody (AA 21-70) (ABIN1450974)

Target: MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MRPS12 Antibody

Binding Specificity: AA 21-70

Purpose: MRP-S12 Antibody

Specificity: MRP-S12 Polyclonal Antibody detects endogenous levels of MRP-S12 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPS12. AA range:21-70

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPS12

Target: MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

Alternative Name: MRPS12

Background:

Synonyms: MRPS12, RPMS12, RPSM12, 28S ribosomal protein S12, mitochondrial, MRP-S12, S12mt, MT-RPS12

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. Th

Gene Name: MRPS12

Protein Name: 28S ribosomal protein S12 mitochondrial

Molecular Weight: 15 kDa

Gene ID: 6183

OMIM: 603021

UniProt: O15235

Pathways: Sensory Perception of Sound