Acetylcholinesterase antibody (AA 551-600)

Catalog No. ABIN1451010

The Rabbit Polyclonal anti-Acetylcholinesterase antibody (ABIN1451010) specifically detects Acetylcholinesterase in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Acetylcholinesterase antibody (AA 551-600) (ABIN1451010)

Target: Acetylcholinesterase (AChE)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acetylcholinesterase antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Acetylcholinesterase Antibody

Binding Specificity: AA 551-600

Purpose: AChE Antibody

Specificity: AChE Polyclonal Antibody detects endogenous levels of AChE protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ACHE. AA range:551-600

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Acetylcholinesterase

Target: Acetylcholinesterase (AChE)

Alternative Name: ACHE

Background:

Synonyms: ACHE, Acetylcholinesterase, AChE

Background: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively

Gene Name: ACHE

Protein Name: Acetylcholinesterase

Molecular Weight: 67 kDa

Gene ID: 43

OMIM: 100740

UniProt: P22303

Pathways: Skeletal Muscle Fiber Development