Atrophin 1 antibody (AA 81-130)

Catalog No. ABIN1451055

The Rabbit Polyclonal anti-Atrophin 1 antibody (ABIN1451055) specifically detects Atrophin 1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Atrophin 1 antibody (AA 81-130) (ABIN1451055)

Target: Atrophin 1 (ATN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Atrophin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Atrophin 1 Antibody

Binding Specificity: AA 81-130

Purpose: Atrophin-1 Antibody

Specificity: Atrophin-1 Polyclonal Antibody detects endogenous levels of Atrophin-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ATN1. AA range:81-130

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Atrophin 1

Target: Atrophin 1 (ATN1)

Alternative Name: ATN1

Background:

Synonyms: ATN1, D12S755E, DRPLA, Atrophin-1, Dentatorubral-pallidoluysian atrophy protein

Background: Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Jul 2016],

Gene Name: ATN1

Protein Name: Atrophin-1

Molecular Weight: 124 kDa

Gene ID: 1822

OMIM: 125370

UniProt: P54259