PDE4C antibody (AA 291-340)

Catalog No. ABIN1451109

The Rabbit Polyclonal anti-PDE4C antibody (ABIN1451109) specifically detects PDE4C in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PDE4C antibody (AA 291-340) (ABIN1451109)

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDE4C Antibody

Binding Specificity: AA 291-340

Purpose: PDE4C Antibody

Specificity: PDE4C Polyclonal Antibody detects endogenous levels of PDE4C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PDE4C. AA range:291-340

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PDE4C

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Alternative Name: PDE4C

Background:

Synonyms: PDE4C, DPDE1, cAMP-specific 3', 5'-cyclic phosphodiesterase 4C, DPDE1, PDE21

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],

Gene Name: PDE4C

Protein Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4C

Molecular Weight: 79 kDa

Gene ID: 5143

OMIM: 600128

UniProt: Q08493

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process