CLCNKA antibody (AA 581-630)

Catalog No. ABIN1451160

The Rabbit Polyclonal anti-CLCNKA antibody (ABIN1451160) specifically detects CLCNKA in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CLCNKA antibody (AA 581-630) (ABIN1451160)

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCNKA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CLCNKA Antibody

Binding Specificity: AA 581-630

Purpose: CLC-KA Antibody

Specificity: CLC-KA Polyclonal Antibody detects endogenous levels of CLC-KA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human CLCNKA. AA range:581-630

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CLCNKA

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Alternative Name: CLCNKA

Background:

Synonyms: CLCNKA, Chloride channel protein ClC-Ka, Chloride channel Ka, ClC-K1

Background: This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: CLCNKA

Protein Name: Chloride channel protein ClC-Ka

Molecular Weight: 75 kDa

Gene ID: 1187

OMIM: 602024

UniProt: P51800

Pathways: Response to Water Deprivation