NARF antibody (AA 262-311)

Catalog No. ABIN1451400

The Rabbit Polyclonal anti-NARF antibody (ABIN1451400) specifically detects NARF in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NARF antibody (AA 262-311) (ABIN1451400)

Target: NARF (Nuclear Prelamin A Recognition Factor (NARF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NARF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NARF Antibody

Binding Specificity: AA 262-311

Purpose: NARF Antibody

Specificity: NARF Polyclonal Antibody detects endogenous levels of NARF protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NARF. AA range:262-311

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NARF

Target: NARF (Nuclear Prelamin A Recognition Factor (NARF))

Alternative Name: NARF

Background:

Synonyms: NARF, Nuclear prelamin A recognition factor, Iron-only hydrogenase-like protein 2, IOP2

Background: Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A.The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It

Gene Name: NARF

Protein Name: Nuclear prelamin A recognition factor

Molecular Weight: 51 kDa

Gene ID: 26502

OMIM: 605349

UniProt: Q9UHQ1