PPP1R16A antibody (AA 362-411)

Catalog No. ABIN1451469

The Rabbit Polyclonal anti-PPP1R16A antibody (ABIN1451469) specifically detects PPP1R16A in WB, ELISA, IHC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for PPP1R16A antibody (AA 362-411) (ABIN1451469)

Target: PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R16A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PPP1R16A Antibody

Binding Specificity: AA 362-411

Purpose: MYPT3 Antibody

Specificity: MYPT3 Polyclonal Antibody detects endogenous levels of MYPT3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PPP1R16A. AA range:362-411

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, IF ICC 1:50-200,ELISA 1:2000-20000,IHC 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PPP1R16A

Target: PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))

Alternative Name: PPP1R16A

Background:

Synonyms: PPP1R16A, MYPT3, Protein phosphatase 1 regulatory subunit 16A, Myosin phosphatase-targeting subunit 3

Background: Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit.The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016],

Gene Name: PPP1R16A

Protein Name: Protein phosphatase 1 regulatory subunit 16A

Molecular Weight: 57 kDa

Gene ID: 84988

OMIM: 609172

UniProt: Q96I34