RASA3 antibody (AA 247-296)

Catalog No. ABIN1451505

The Rabbit Polyclonal anti-RASA3 antibody (ABIN1451505) specifically detects RASA3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RASA3 antibody (AA 247-296) (ABIN1451505)

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RASA3 Antibody

Binding Specificity: AA 247-296

Purpose: GAP1-InsP4 BP Antibody

Specificity: GAP1-InsP4 BP Polyclonal Antibody detects endogenous levels of GAP1-InsP4 BP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RASA3

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Alternative Name: RASA3

Background:

Synonyms: RASA3, Ras GTPase-activating protein 3, GAP1(IP4BP), Ins P4-binding protein

Background: This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Gene Name: RASA3

Protein Name: Ras GTPase-activating protein 3

Molecular Weight: 95 kDa

Gene ID: 22821

OMIM: 605182

UniProt: Q14644