RAD51C antibody (AA 161-210)

Catalog No. ABIN1451826

The Rabbit Polyclonal anti-RAD51C antibody (ABIN1451826) specifically detects RAD51C in WB, ELISA, IHC and IF. The antibody is reactive with Human and Monkey samples.

Quick Overview for RAD51C antibody (AA 161-210) (ABIN1451826)

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD51C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RAD51C Antibody

Binding Specificity: AA 161-210

Purpose: Rad51C Antibody

Specificity: Rad51C Polyclonal Antibody detects endogenous levels of Rad51C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human RAD51C. AA range:161-210

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Alternative Name: RAD51L2

Background:

Synonyms: RAD51C, RAD51L2, DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2

Background: RAD51 paralog C(RAD51C) Homo sapiens This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Gene Name: RAD51C

Protein Name: DNA repair protein RAD51 homolog 3

Molecular Weight: 42 kDa

Gene ID: 5889

OMIM: 602774

UniProt: O43502

Pathways: DNA Damage Repair