TAO Kinase 3 antibody (AA 531-580)

Catalog No. ABIN1451898

The Rabbit Polyclonal anti-TAO Kinase 3 antibody (ABIN1451898) specifically detects TAO Kinase 3 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TAO Kinase 3 antibody (AA 531-580) (ABIN1451898)

Target: TAO Kinase 3 (TAOK3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAO Kinase 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TAO Kinase 3 Antibody

Binding Specificity: AA 531-580

Purpose: JIK Antibody

Specificity: JIK Polyclonal Antibody detects endogenous levels of JIK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human TAOK3. AA range:531-580

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TAO Kinase 3

Target: TAO Kinase 3 (TAOK3)

Alternative Name: TAOK3

Background:

Synonyms: TAOK3, DPK, JIK, KDS, MAP3K18, Serine/threonine-protein kinase TAO3, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhi

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,

Gene Name: TAOK3

Protein Name: Serine/threonine-protein kinase TAO3

Molecular Weight: 105 kDa

Gene ID: 51347

UniProt: Q9H2K8