CD70 antibody (AA 68-117)

Catalog No. ABIN1451922

The Rabbit Polyclonal anti-CD70 antibody (ABIN1451922) specifically detects CD70 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CD70 antibody (AA 68-117) (ABIN1451922)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD70 Antibody

Binding Specificity: AA 68-117

Purpose: CD70 Antibody

Specificity: CD70 Polyclonal Antibody detects endogenous levels of CD70 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human CD70. AA range:68-117

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background:

Synonyms: CD70, CD27L, CD27LG, TNFSF7, CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD antigen CD70

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008],

Gene Name: CD70

Protein Name: CD70 antigen

Molecular Weight: 21 kDa

Gene ID: 970

OMIM: 602840

UniProt: P32970

Pathways: Cancer Immune Checkpoints