IL17RC antibody (AA 721-770)

Catalog No. ABIN1451946

The Rabbit Polyclonal anti-IL17RC antibody (ABIN1451946) specifically detects IL17RC in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IL17RC antibody (AA 721-770) (ABIN1451946)

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RC Antibody

Binding Specificity: AA 721-770

Purpose: IL-17RC Antibody

Specificity: IL-17RC Polyclonal Antibody detects endogenous levels of IL-17RC protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IL17RC

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Alternative Name: IL17RC

Background:

Synonyms: IL17RC, Interleukin-17 receptor C, IL-17 receptor C, IL-17RC, Interleukin-17 receptor homolog, IL17Rhom, Interleukin-17 receptor-like protein, IL-17RL, ZcytoR14

Background: This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011],

Gene Name: IL17RC

Protein Name: Interleukin-17 receptor C

Molecular Weight: 86 kDa

Gene ID: 84818

OMIM: 610925

UniProt: Q8NAC3