SIRT2 antibody (AA 321-370)

Catalog No. ABIN1452045

The Rabbit Polyclonal anti-SIRT2 antibody (ABIN1452045) specifically detects SIRT2 in WB, IHC and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for SIRT2 antibody (AA 321-370) (ABIN1452045)

Target: SIRT2 (Sirtuin 2 (SIRT2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SIRT2 Antibody

Binding Specificity: AA 321-370

Purpose: SIRT2 Antibody

Specificity: SIRT2 Polyclonal Antibody detects endogenous levels of SIRT2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SIRT2. AA range:321-370

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SIRT2

Target: SIRT2 (Sirtuin 2 (SIRT2))

Alternative Name: SIRT2

Background:

Synonyms: SIRT2, SIR2L, SIR2L2, NAD-dependent protein deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, SIR2-like protein 2

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010],

Gene Name: SIRT2

Protein Name: NAD-dependent protein deacetylase sirtuin-2

Molecular Weight: 43 kDa

Gene ID: 22933

OMIM: 604480

UniProt: Q8IXJ6