Adrenomedullin antibody (AA 51-100)

Catalog No. ABIN1452903

The Rabbit Polyclonal anti-Adrenomedullin antibody (ABIN1452903) specifically detects Adrenomedullin in IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Adrenomedullin antibody (AA 51-100) (ABIN1452903)

Target: Adrenomedullin (ADM)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adrenomedullin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Adrenomedullin Antibody

Binding Specificity: AA 51-100

Purpose: ADM Antibody

Specificity: ADM Polyclonal Antibody detects endogenous levels of ADM protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ADM. AA range:51-100

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Adrenomedullin

Target: Adrenomedullin (ADM)

Alternative Name: ADM

Target Type: Hormone

Background:

Synonyms: ADM, AM, ADM

Background: The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014],

Gene Name: ADM

Protein Name: ADM

Molecular Weight: 20 kDa

Gene ID: 133

OMIM: 103275

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation