MIP antibody (AA 95-144)

Catalog No. ABIN1452936

The Rabbit Polyclonal anti-MIP antibody (ABIN1452936) specifically detects MIP in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MIP antibody (AA 95-144) (ABIN1452936)

Target: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MIP Antibody

Binding Specificity: AA 95-144

Purpose: AQP0 Antibody

Specificity: AQP0 Polyclonal Antibody detects endogenous levels of AQP0 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human AQP0. AA range:95-144

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MIP

Target: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Alternative Name: AQP0

Background:

Synonyms: MIP, AQP0, Lens fiber major intrinsic protein, Aquaporin-0, MIP26, MP26

Background: Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13. [provided by RefSeq, Jul 2008],

Gene Name: MIP

Protein Name: Lens fiber major intrinsic protein

Molecular Weight: 28 kDa

Gene ID: 4284

OMIM: 154050

UniProt: P30301