BMP5 antibody (AA 114-163)

Catalog No. ABIN1452969

The Rabbit Polyclonal anti-BMP5 antibody (ABIN1452969) specifically detects BMP5 in WB, IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for BMP5 antibody (AA 114-163) (ABIN1452969)

Target: BMP5 (Bone Morphogenetic Protein 5 (BMP5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-BMP5 Antibody

Binding Specificity: AA 114-163

Purpose: BMP-5 Antibody

Specificity: BMP-5 Polyclonal Antibody detects endogenous levels of BMP-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human BMP-5. AA range:114-163

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BMP5

Target: BMP5 (Bone Morphogenetic Protein 5 (BMP5))

Alternative Name: BMP-5

Background:

Synonyms: BMP5, Bone morphogenetic protein 5, BMP-5

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers.This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016],

Gene Name: BMP5

Protein Name: Bone morphogenetic protein 5

Molecular Weight: 51 kDa

Gene ID: 653

OMIM: 112265

UniProt: P22003

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process