Calpain 2 antibody (AA 305-354)

Catalog No. ABIN1453011

The Rabbit Polyclonal anti-Calpain 2 antibody is suitable to detect Calpain 2 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for Calpain 2 antibody (AA 305-354) (ABIN1453011)

Target: Calpain 2 (CAPN2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Calpain 2 Antibody

Binding Specificity: AA 305-354

Purpose: Calpain 2 Antibody

Specificity: Calpain 2 Polyclonal Antibody detects endogenous levels of Calpain 2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Calpain 2. AA range:305-354

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Calpain 2

Target: Calpain 2 (CAPN2)

Alternative Name: Calpain 2

Background:

Synonyms: CAPN2; CANPL2; Calpain-2 catalytic subunit; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpain

Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit.This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

Gene Name: CAPN2

Protein Name: Calpain-2 catalytic subunit

Molecular Weight: 80 kDa

Gene ID: 824

OMIM: 114230

UniProt: P17655