E2F5 antibody (AA 93-142)

Catalog No. ABIN1453215

The Rabbit Polyclonal anti-E2F5 antibody (ABIN1453215) specifically detects E2F5 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for E2F5 antibody (AA 93-142) (ABIN1453215)

Target: E2F5

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E2F5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-E2F5 Antibody

Binding Specificity: AA 93-142

Purpose: E2F-5 Antibody

Specificity: E2F-5 Polyclonal Antibody detects endogenous levels of E2F-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human E2F-5. AA range:93-142

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for E2F5

Target: E2F5

Alternative Name: E2F-5

Background:

Synonyms: E2F5, Transcription factor E2F5, E2F-5

Background: The protein encoded byThis gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 inter

Gene Name: E2F5

Protein Name: Transcription factor E2F5

Molecular Weight: 37 kDa

Gene ID: 1875

OMIM: 600967

UniProt: Q15329