EEA1 antibody (AA 205-254)

Catalog No. ABIN1453230

The Rabbit Polyclonal anti-EEA1 antibody (ABIN1453230) specifically detects EEA1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for EEA1 antibody (AA 205-254) (ABIN1453230)

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EEA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EEA1 Antibody

Binding Specificity: AA 205-254

Purpose: EEA1 Antibody

Specificity: EEA1 Polyclonal Antibody detects endogenous levels of EEA1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EEA1

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Alternative Name: EEA1

Background:

Synonyms: EEA1, ZFYVE2, Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2

Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,

Gene Name: EEA1

Protein Name: Early endosome antigen 1

Molecular Weight: 162 kDa

Gene ID: 8411

OMIM: 605070

UniProt: Q15075

Pathways: Toll-Like Receptors Cascades