Fatty Acid Synthase antibody (AA 1478-1527)

Catalog No. ABIN1453278

The Rabbit Polyclonal anti-Fatty Acid Synthase antibody (ABIN1453278) specifically detects Fatty Acid Synthase in WB, IHC, IF and ELISA. The antibody is reactive with Human samples.

Quick Overview for Fatty Acid Synthase antibody (AA 1478-1527) (ABIN1453278)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-Fatty Acid Synthase Antibody

Binding Specificity: AA 1478-1527

Purpose: Fatty Acid Synthase Antibody

Specificity: Fatty Acid Synthase Polyclonal Antibody detects endogenous levels of Fatty Acid Synthase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Fatty Acid Synthase. AA range:1478-1527

Isotype: IgG

Application Details

Application Notes: IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: Fatty Acid Synthase

Background:

Synonyms: FASN, FAS, Fatty acid synthase

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008],

Gene Name: FASN

Protein Name: Fatty acid synthase

Molecular Weight: 273 kDa

Gene ID: 2194

OMIM: 600212

UniProt: P49327

Pathways: AMPK Signaling