Indian Hedgehog antibody (AA 209-258)

Catalog No. ABIN1453452

The Rabbit Polyclonal anti-Indian Hedgehog antibody (ABIN1453452) specifically detects Indian Hedgehog in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Indian Hedgehog antibody (AA 209-258) (ABIN1453452)

Target: Indian Hedgehog (IHH)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Indian Hedgehog antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Indian Hedgehog Antibody

Binding Specificity: AA 209-258

Purpose: Ihh Antibody

Specificity: Ihh Polyclonal Antibody detects endogenous levels of Ihh protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Ihh. AA range:209-258

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Indian Hedgehog

Target: Indian Hedgehog (IHH)

Alternative Name: Ihh

Background:

Synonyms: IHH, Indian hedgehog protein, IHH, HHG-2

Background: This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis.The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015],

Gene Name: IHH

Protein Name: Indian hedgehog protein

Molecular Weight: 45 kDa

Gene ID: 3549

OMIM: 600726

UniProt: Q14623

Pathways: Hedgehog Signaling