IL-11 antibody (AA 27-76)

Catalog No. ABIN1453455

The Rabbit Polyclonal anti-IL-11 antibody (ABIN1453455) specifically detects IL-11 in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IL-11 antibody (AA 27-76) (ABIN1453455)

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-11 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IL-11 Antibody

Binding Specificity: AA 27-76

Purpose: IL-11 Antibody

Specificity: IL-11 Polyclonal Antibody detects endogenous levels of IL-11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human IL-11. AA range:27-76

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IL-11

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Alternative Name: IL-11

Background:

Synonyms: IL11, Interleukin-11, IL-11, Adipogenesis inhibitory factor, AGIF, Oprelvekin

Background: The protein encoded byThis gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012],

Gene Name: IL11

Protein Name: Interleukin-11

Molecular Weight: 21 kDa

Gene ID: 3589

OMIM: 147681

UniProt: P20809

Pathways: JAK-STAT Signaling, Negative Regulation of Hormone Secretion