ITGA3 antibody (AA 482-531)

Catalog No. ABIN1453518

The Rabbit Polyclonal anti-ITGA3 antibody (ABIN1453518) specifically detects ITGA3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ITGA3 antibody (AA 482-531) (ABIN1453518)

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ITGA3 Antibody

Binding Specificity: AA 482-531

Purpose: Integrin α3 Antibody

Specificity: Integrin α3 Polyclonal Antibody detects endogenous levels of Integrin α3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Integrin alpha3. AA range:482-531

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ITGA3

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Alternative Name: Integrin Alpha3

Background:

Synonyms: ITGA3, MSK18, Integrin alpha-3, CD49 antigen-like family member C, FRP-2, Galactoprotein B3, GAPB3, VLA-3 subunit alpha, CD antigen CD49c

Background: integrin subunit alpha 3(ITGA3) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015],

Gene Name: ITGA3

Protein Name: Integrin alpha-3

Molecular Weight: 118 kDa

Gene ID: 3675

OMIM: 605025

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex