CCL3 antibody (AA 26-75)

Catalog No. ABIN1453575

The Rabbit Polyclonal anti-CCL3 antibody (ABIN1453575) specifically detects CCL3 in ELISA, IHC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for CCL3 antibody (AA 26-75) (ABIN1453575)

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CCL3 Antibody

Binding Specificity: AA 26-75

Purpose: MIP-1α Antibody

Specificity: MIP-1α Polyclonal Antibody detects endogenous levels of MIP-1α protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MIP-1alpha. AA range:26-75

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CCL3

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Alternative Name: MIP-1Alpha

Background:

Synonyms: CCL3, G0S19-1, MIP1A, SCYA3, C-C motif chemokine 3, G0/G1 switch regulatory protein 19-1, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, PAT 464.1, SIS-beta, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein

Background: This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010],

Gene Name: CCL3

Protein Name: C-C motif chemokine 3

Molecular Weight: 10 kDa

Gene ID: 6348

OMIM: 182283

UniProt: P10147

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy