MTHFR antibody (AA 314-363)

Catalog No. ABIN1453587

The Rabbit Polyclonal anti-MTHFR antibody (ABIN1453587) specifically detects MTHFR in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Monkey samples.

Quick Overview for MTHFR antibody (AA 314-363) (ABIN1453587)

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTHFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MTHFR Antibody

Binding Specificity: AA 314-363

Purpose: MTHFR Antibody

Specificity: MTHFR Polyclonal Antibody detects endogenous levels of MTHFR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MTHFR

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Alternative Name: MTHFR

Background:

Synonyms: MTHFR, Methylenetetrahydrofolate reductase

Background: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009],

Gene Name: MTHFR

Protein Name: Methylenetetrahydrofolate reductase

Molecular Weight: 74 kDa

Gene ID: 4524

OMIM: 607093

UniProt: P42898

Pathways: Methionine Biosynthetic Process